Screening for emphysema via exhaled volatile organic compounds

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Screening for emphysema via exhaled volatile organic compounds.

Chronic obstructive pulmonary disease (COPD)/emphysema risk groups are well defined and screening allows for early identification of disease. The capability of exhaled volatile organic compounds (VOCs) to detect emphysema, as found by computed tomography (CT) in current and former heavy smokers participating in a lung cancer screening trial, was investigated. CT scans, pulmonary function tests ...

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BACKGROUND An effective screening tool for colorectal cancer is still lacking. Analysis of the volatile organic compounds (VOCs) linked to cancer is a new frontier in cancer screening, as tumour growth involves several metabolic changes leading to the production of specific compounds that can be detected in exhaled breath. This study investigated whether patients with colorectal cancer have a s...

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Non-invasive phenotyping using exhaled volatile organic compounds in asthma.

BACKGROUND Breath volatile organic compounds (VOCs) may be useful for asthma diagnosis and phenotyping, identifying patients who could benefit from personalised therapeutic strategies. The authors aimed to identify specific patterns of breath VOCs in patients with asthma and in clinically relevant disease phenotypes. METHODS Breath samples were analysed by gas chromatography-mass spectrometry...

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Nonvolatile, semivolatile, or volatile: redefining volatile for volatile organic compounds.

UNLABELLED Although widely used in air quality regulatory frameworks, the term "volatile organic compound" (VOC) is poorly defined. Numerous standardized tests are currently used in regulations to determine VOC content (and thus volatility), but in many cases the tests do not agree with each other, nor do they always accurately represent actual evaporation rates under ambient conditions. The pa...

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ژورنال

عنوان ژورنال: Journal of Breath Research

سال: 2011

ISSN: 1752-7155,1752-7163

DOI: 10.1088/1752-7155/5/4/046009